Cyclophilin

Maily β example

Basic info about members of the topology level:

 

 

Resolution ()

length

SSE content (%)

1awg

1,58

164

43

1a33

2,15

174

44

1cyn

1,85

178

48

1qoi

2,0

173

45

1lop

1,8

164

48

1qng

2,1

170

45

2rmc A

1,64

182

47

1dyw

1,8

172

43

1ihg

1,8

364

56

 

Serverss results:

 

Number in parentheses in column Another true positives means number of retrieved true positives
First columns of the tables contain PDB ID of structures.

Dali

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

yes

3.

4 min

1a33

yes

yes

3.

3 min

1cyn

yes

yes

3.

5 min

1qoi

yes

yes

3.

5 min

1lop

yes

yes

no

4 min

1qng

yes

yes

3.

4 min

2rmc

yes

yes

no

9 min

1dyw

yes

yes

3.

4 mim

1ihg

yes

yes

3.

4 min

 

Vast

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

Yes(1)

no

12 min

1a33

No

Yes(2)

no

10 min

1cyn

No

Yes(2)

no

8 min

1qoi

No

Yes(2)

no

8 min

1lop

yes

Yes(1)

no

10 min

1qng

No

Yes(2)

no

10 ,in

2rmc

No

Yes(2)

no

5 min

1dyw

No

Yes (2)

no

10 min

1ihg

no

Yes(2)

3.

25 min

 

Top

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

Yes

Yes (6)

8

9 min

1a33

Yes

Yes (6)

8

9 min

1cyn

Yes

Yes (6)

no

9 min

1qoi

Yes

Yes (6)

8

7 min

1lop

yes

Yes(1)

no

10 min

1qng

no

Yes(5)

6.

8 min

2rmc

Yes

Yes (6)

8

9 min

1dyw

yes

Yes (6)

8

9 min

1ihg

no

Yes(3)

no

8 min

 

Tops

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

Yes(4)

6

2 min

1a33

yes

Yes(4)

6

2 min

1cyn

yes

Yes(4)

6

4 min

1qoi

no

Yes(5, 1>10)

6

2 min

1lop

yes

Yes(5>10score)

5

5 min

1qng

no

Yes(5)

6

3 min

2rmc

Yes

Yes(3)

5

3 min

1dyw

No

Yes(5)

6

3 min

1ihg

No

Yes(1>10)

2

4 min

 


Topscan

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

Yes(4)

6

Seconds

1a33

yes

Yes(4)

6

Seconds

1cyn

yes

Yes(4)

6

seconds

1qoi

no

Yes(5)

6

Seconds

1lop

yes

Yes(4)

4

Seconds

1qng

no

Yes(5)

6

Seconds

2rmc

yes

Yes(4)

6

seconds

1dyw

no

Yes(5)

6

Seconds

1ihg

no

Yes(4)

5

1 min

 

 

Lock

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

no

Yes (1)

2

8 min

1a33

no

Yes (1)

2

9 min

1cyn

no

Yes (1)

2

10 min

1qoi

no

Yes (1)

2

9 min

1lop

no

Yes (1)

2

9 min

1qng

no

Yes (1)

2

8 min

2rmc

yes

no

2

8 min

1dyw

no

Yes (1)

2

8 min

1ihg

no

Yes (1)

2

15 min

 

CE

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

Yes(2)

4(only one)

 

1a33

yes

Yes(2)

4(only one)

 

1cyn

yes

Yes(2)

4(only one)

 

1qoi

yes

Yes(2)

4(only one)

 

1lop

yes

Yes(2)

no

 

1qng

yes

Yes(2)

4(only one)

 

2rmc

yes

Yes(2)

4(only one)

 

1dyw

yes

Yes(2)

4(only one)

 

1ihg

yes

Yes (many)

After all true hits

20 hours

CE processing times are unknown for most of the structures, because we used pre-computed results (see paper).

Matras

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

Yes (2)

4

11 min

1a33

no

Yes(3)

4

11 min

1cyn

no

Yes(3)

4

20 min

1qoi

no

Yes(3)

4

45 min

1lop

yes

Yes(2)

4

11 min

1qng

no

Yes(3)

4

37 min

2rmc

no

Yes(3)

4

48 min

1dyw

no

Yes(3)

4

19 min

1ihg

yes

Yes (2)

4

41 min

Times are probably biased with uploading all structures together.

Dejavu

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

yes

Yes(13)

15

54 min

1a33

yes

Yes(13)

15

12 min

1cyn

yes

Yes(13)

15

15 min

1qoi

yes

Yes(13)

no

5 min

1lop

yes

Yes(13)

15

20 min

1qng

yes

Yes(13)

no

16 min

2rmc

yes

Yes(13)

15

5 min

1dyw

yes

Yes(13)

15

21 min

1ihg

yes

Yes(11)

no

22 min


Number of true positives doesnt mean in this particular case the number of matched structures,

but the number of matched chains.

SSM

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

Yes

Yes (94)

no

2

1a33

yes

Yes (94)

no

2

1cyn

No

Yes(90)

no

2

1qoi

No

Yes (93)

no

2

1lop

Yes

No

no

3

1qng

Yes

Yes(88)

no

2

2rmc

No

Yes (94)

no

2

1dyw

Yes

Yes(93)

no

2

1ihg

Yes

Yes (93)

no

2

Number of true positives doesnt mean in this particular case the number of matched structures,

but the number of matched chains.

                                                                                                                                 Pride

 

Found itself on first position

Another true positive

Position of first false positive

Time

1awg

Yes

Yes(5)

7

Sec

1a33

No

Yes(7)

8

Sec

1cyn

Yes

Yes(5)

7

Sec

1qoi

Yes

Yes(7)

9

Sec

1lop

Yes

Yes(6)

5

Sec

1qng

Yes

Yes(6)

6

Sec

2rmc

No

Yes(8)

9

Sec

1dyw

Yes

Yes(6)

8

Sec

1ihg

No

No

1

Sec

 

Summary

Server

Trivial solution found (itself)

Non-trivial solutions found

Rank of first false positive

Time
(minutes)

CE

9

9

0 or 4

 

Dali

9

9

0 or 3

5-10

Dejavu

9

9

No or 15

5-55

Lock

1

8

2

5-15

Matras

9

9

3

10-45

Pride

6

8

1-9

<1

SSM

6

8

0

2-3

Top

7

9

6-8

5-10

Tops

5

9

2-6

<5

Topscan

5

9

4-6

<1

Vast

2

9

0 or 3

5-25




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