Proliferating Cell Nuclear Antigen
-
α-β class example


Basic info about members of the topology level:

just one these structures in the Lock database

Structure
Resolution (Å)
Length (aa)
SSE content (%)
1axc
2.6
249
64.3
1b77
2.1
228
53.9
1czd
2.45
228
55.3
1dml
2.7
267
51.7
1ge8
2.1
238
65.1
1plq
2.3
258
56.3

Number in parentheses in column” Another true positives” means number of retrieved true positives.
First columns of the tables contain PDB ID of structures.


CE

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (5)
4
12
1b77
Yes
Yes (5)
3
12
1czd
Yes
Yes (5)
3
14
1dml
Yes
Yes (5)
5
5
1ge8
Yes
Yes (5)
3
14
1plq
Yes
Yes (5)
4
9

Dali

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (3)
3
9
1b77
Yes
Yes (3)
3
10
1czd
Yes
Yes (3)
5
9
1dml
Yes
Yes (2)
3
10
1ge8
Yes
Yes (3)
3
14
1plq
Yes
Yes (4)
4
9

Dejavu

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (5)
4
4
1b77
Yes
Yes (4)
4
5
1czd
Yes
Yes (4)
6
5
1dml
Yes
Yes (3)
3
3
1ge8
Yes
Yes (5)
4
2
1plq
Yes
Yes (5)
4
3

Lock

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
No
Yes (1)
2
13
1b77
No
Yes (1)
1
11
1czd
No
Yes (1)
2
12
1dml
No
Yes (1)
2
14
1ge8
No
Yes (1)
2
15
1plq
Yes
no
2
17

Matras

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (3)
3
19
1b77
Yes
Yes (3)
4
17
1czd
No
Yes (4)
4
12
1dml
Yes
Yes (3)
4
27
1ge8
No
Yes (4)
3
17
1plq
Yes
Yes (3)
3
17

Pride

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
No
2
Sec
1b77
Yes
Yes (1)
3
Sec
1czd
Yes
Yes (1)
3
Sec
1dml
Yes
No
2
Sec
1ge8
No
Yes (1)
3
Sec
1plq
No
Yes (2)
2
Sec

SSM

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (5)
-
Sec
1b77
Yes
Yes (4)
-
Sec
1czd
Yes
Yes (4)
-
Sec
1dml
Yes
Yes (4)
-
Sec
1ge8
Yes
Yes (5)
-
Sec
1plq
Yes
Yes (5)
-
Sec

Top

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (3)
-
ND
1b77
Yes
Yes (3)
-
ND
1czd
Yes
Yes (3)
-
ND
1dml
Yes
No
-
ND
1ge8
No
Yes (4)
-
ND
1plq
Yes
Yes (4)
-
ND
ND – not determined

Tops

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
No
Yes (1)*
1
5
1b77
No
Yes (1)*
1
5
1czd
No
Yes (1)*
1
5
1dml
No
Yes (1)*
1
5
1ge8
No
Yes (1)*
1
5
1plq
No
No
1
5
* true positive with non-significant score
Topscan

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
Yes
Yes (1)
3
Sec
1b77
No
Yes (2)
2
Sec
1czd
No
Yes (2)
1
Sec
1dml
No
Yes (2)
3
Sec
1ge8
No
Yes (2)
3
Sec
1plq
Yes
Yes (1)
3
Sec

Vast

Found itself on first position
Another true positive
First false positive
Time (min)
1axc
No
Yes (3)
3
20
1b77
Yes
Yes (1)
2
20
1czd
No
Yes (2)
2
20
1dml
Yes
Yes (2)
3
20
1ge8
No
Yes (2)
2
24
1plq
Yes
Yes (2)
3
25



Server
Trivial solution found (itself)
Non-trivial solutions found
Rank of first false positive
Time (minutes)
CE
6
6
3-5
5-15
DALI
6
6
3-5
10-15
DEJAVU
6
6
3-5
5
LOCK
1
5
1-2
10-20
MATRAS
4
6
3-4
15-30
PRIDE
4
4
2-3
Sec
SSM
6
6
-
Sec
TOP
5
5
-
ND
TOPS
6
5
1
5
TOPSCAN
2
6
1-3
Sec
VAST
3
6
2-3
20-25