SBNet

SBNet - Positions available


NOTE: if you want to announce a job opening, please use this form !


For jobs in crystallography check the lists of the IUCr, ACA, or BCA. The IUCr page also contains links to additional relevant sites. For jobs in NMR, look here or here. Some available postdoc and PhD positions can be found at www.FindAPostDoc.com and at www.FindAPhD.com. Various job opportunities can be found at the "Career Center" of the Science Advisory Board web site(here).


Note: positions in Scandinavia are shown on a coloured background.


Postdoctoral position available

Date posted: 25 January, 2010

Deadline for applications: 10 February, 2010

Announcement will be removed: 11 February, 2010

Post-doctoral position in membrane protein crystallography

DEADLINE FOR APPLICATIONS: 10 February 2010

TYPE OF POSITION: post-doc

INSTITUTION/DEPARTMENT: University of Gothenburg, Department of Chemistry

CONTACT PERSON: Dr Susanna Törnroth-Horsefield
Medicinaregatan 9E
Lundberg laboratory
SE-405 30 Gothenburg
+46-31-786 39 23
tornroth@chem.gu.se

DESCRIPTION/REQUIREMENTS: A postdoc position in membrane protein 
crystallography is available in the group of Dr 
Susanna Törnroth-Horsefield, University of 
Gothenburg. The position is funded for 1 year 
and may be extended up to two years depending on 
the availability of further funding and 
satisfactory performance. 

The group is situated at the Lundberg laboratory 
which contains a membrane protein structural 
biology research platform with excellent 
facilities and a stimulating research 
environment.

The research will focus on membrane proteins 
that are involved in Type 2 diabetes, the most 
common metabolic disease in the world, in 
particular the uncoupling proteins (UCP) and 
transhydrogenase (TH). The work will involve 
expression and purification as well as 
crystallisation and structural determination. 

The ideal candidate has a PhD in Structural 
Biology, Biochemistry or equivalent and has well-
documented experience in protein purification 
and protein crystallography. Experience with 
membrane proteins is an advantage. The ability 
to work in a group is a requirement. Applicants 
who received their PhD within the last three 
years will be favoured. The position is 
available immediately. 

APPLICATION PROCEDURE: The application should be written in English and 
include a CV, short description of scientific 
track record, publication list and the names and 
email addresses of two personal references who 
can comment on the applicants scientific merits 
and ability to work in a research group.  

The closing date for the application is the 10th 
of February 2010.
Please mark the application with: Ref Nr: E36 
223/10.

The application should be sent to:
Registrar
University of Gothenburg
Box 100
405 30 Gothenburg


ADDITIONAL INFORMATION: For further information about the research 
group, project and position, please contact 
Susanna Törnroth-Horsefield directly at 
tornroth@chem.gu.se


Postdoc opportunity in structural immunology at EMBL Hamburg

Date posted: 25 January, 2010

Deadline for applications: 31 January, 2010

Announcement will be removed: 1 February, 2010

INSTITUTION/DEPARTMENT: EMBL Hamburg, Germany

CONTACT PERSON: General enquiries may be sent to jobs@embl.de.

DESCRIPTION/REQUIREMENTS: The Meijers lab at the EMBL in Hamburg, Germany is
looking for an outstanding post-doctoral scientist
to work on structural aspects of the assembly and
organization of the immunological synapse. We use
a range of methodologies including cell biology,
protein biochemistry, protein engineering, X-ray
crystallography and bioinformatics to study the
weak and specific interactions within the
immunological synapse. The laboratory has access
to state of the art protein production and
characterization facilities. It will form an
integral part of the new PETRA3 facility which is
a new source of highly brilliant synchrotron
radiation. Further information on the research
performed in the lab can be found at:

http://www.embl-hamburg.de/research/unit/meijers/index.html

The ideal candidate should have a PhD in
biochemistry or cell biology and extensive
experience in protein expression and purification.
Previous experience in protein structure
determination would be an advantage. The candidate
should have a willingness to develop new
techniques in protein engineering that will open
new avenues to study the dynamics and signaling of
cell surface receptors.

An initial contract of 2 years will be offered to
the successful candidate. This can be renewed
depending on the circumstances at the time of review. 



APPLICATION PROCEDURE: To apply please email a detailed CV, a statement
of research interests and names (incl. e-mail
address) of three potential referees by email
quoting ref. no. W/09/PD/0103 in the subject line,
to: application@embl.de.  

ADDITIONAL INFORMATION: The European Molecular Biology Laboratory (EMBL)
is an inclusive, equal opportunity employer
offering attractive conditions and benefits
appropriate to an international research
organisation. 

DEADLINE FOR APPLICATIONS: 31/1/2010

TYPE OF POSITION: Post-doc


Postdoctoral Position at the University of Wuerzburg

Date posted: 25 January, 2010

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

A postdoctoral position in
Structural Biology of the Spliceosomal Assembly Machinery

is available at the Biocenter of the University of Wuerzburg, Germany, within the department of Biochemistry.
The successful candidate will participate in all stages of crystallographic structure determination from cloning, 
protein expression and purification to synchrotron data collection, processing and model building.

The following qualifications will be required:

- a PhD degree
- experience in protein expression and purification
- experience in data collection and processing
- cumputing skills (scripting languages, linux system administration) would be an advantage.

We offer an initial 2 year contract, extendable depending on project success. Payment will be in accordance with German public service 
positions (TV?D E13), including extensive social security plans. More information about the department and the biocenter is available 
on the respective web sites at:

www.biozentrum.de

Please send your application including a letter of interest, a CV and names of two references to:

Clemens.Grimm@biozentrum.uni-wuerzburg.de


The University of Wuerzburg is an equal opportunity employer with an affirmative action program for the disabled. 


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PhD student position available

Date posted: 25 January, 2010

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

The Experiments Division designs, constructs and runs the ESRF experimental stations (= beamlines). Within this division the 
“Structure Biology group” (Grenoble) is now seeking to recruit a:

PhD Thesis Student (m/f)
Subject: Structure-based design of an efficient biosensor for 2,4 dinitrotoluene

General Framework:
A PhD studentship is available in the Structural Biology Group at the ESRF.  The goal is to use the techniques of Molecular and 
Structural Biology to develop an efficient and specific biosensor for the xenobiotic 2,4-dinitrotoluene and to elucidate the 
mechanism of activation of the LysR transcription factor DntR. The studies carried out during the studentship will build on work 
already carried out in our laboratory and will, in particular, focus on the analysis of the three-dimensional structures of various 
constructs and mutants of DntR using X-ray Crystallography and Small Angle X-ray Scattering.
The studentship is based in the Structural Biology Group at the ESRF which provides state of the art facilities through the Partnership 
for Structural Biology (www.psb-grenoble.eu). The work will involve close collaboration with the group of Prof. Peter Brzezinski, 
Department of Biochemistry and Biophysics, Stockholm University, Sweden and Dr. Cyril Dian, Institut de Biologie Structurale, Grenoble. 
The successful candidate will register for a Ph.D. at the Université Joseph Fourier, Grenoble.

Description of the thesis work:
The studentship will provide extensive training in Molecular Biology and two of the most important techniques in Structural Biology – 
X-ray Crystallography and Small Angle X-ray Scattering. Specific training will be given in:
*Cloning genes and site directed mutagenesis
*Protein expression and purification
*Crystallisation and the crystal structure determination of proteins
*Small Angle X-ray Scattering
*Complementary techniques such as isothermal titration calorimetry  

Place of Work:	ESRF in Grenoble
Supervisor:	Dr. Gordon Leonard  (+33 (0)4 76 88 23 94;  leonard@esrf.fr)

General Conditions:
You should hold a degree in Physics allowing enrolment for a PhD, such as an MSc, Master 2 de Recherche, Laurea or equivalent. Contract 
of two years renewable (subject to satisfactory progress) for one year. Gross salary around 2268 €/month. (The applicant will be responsible 
for arranging his/her academic registration and for paying the fees (if any)). The ESRF is an equal opportunity employer and encourages 
applications from disabled persons.
If you are interested, please send us an e-mail (recruitment@esrf.fr) with your address, and we will provide you with an application form. 
Or print out an application form on the World Wide Web http://www.esrf.fr/Jobs/Applying. In addition to the application form, you should 
provide us with a detailed CV and the names of two referees.

Ref. CFR356 - Deadline for returning application forms: 14 February 2010

All applications received after the deadline may be considered for the selected vacancy if not filled or for future similar positions.

The ESRF is a multinational research institute, situated in Grenoble, France and financed by 19 countries mostly European. It operates 
a powerful synchrotron X-ray source with some 30 beamlines (instruments) covering a wide range of scientific research in fields such as 
biology and medicine, chemistry, earth and environmental sciences, materials and surface science, and physics. Research at the ESRF is 
carried out by several thousand external users each year from universities, public research laboratories and industry, and by the ESRF's 
own scientists. The ESRF employs about 600 staff and is organized as a French société civile. The working language of the ESRF is English.


Postdoctoral position available

Date posted: 25 January, 2010

Deadline for applications: 1 February, 2010

Announcement will be removed: 2 February, 2010

Postdoctoral Program at MAX-lab

The MAX-laboratory is a Swedish National Laboratory in Lund, Sweden. It presently consists of three electron storage rings. It provides 
photons from IR up to the hard X-ray regime and serves 800 scientists a year. MAX-lab is in the process of constructing a new facility, 
MAX IV, in the Brunnshög area of Lund. The new facility will consist of an ultra-low emittance 530 m circumference 3 GeV storage ring, 
a 90 m circumference 1.5 GeV storage ring, a 300 m long linear accelerator and a short pulse facility.

In the perspective of the ongoing research activities and the planning for the MAX IV facility, MAX-lab will now accelerate the 
Postdoctoral program and solicits applications for such positions. PostDoc positions have a maximum duration of 2 year. The economic 
level is 21 290 Sek per month (tax free). Eligible for PostDoc positions are scientists with a doctors degree awarded not more than 
5 years before the application date.

PostDoc projects can be proposed in the entire spectrum of activities at the laboratory including research in the soft or hard energy 
regime, accelerator physics, instrumentation, nuclear physics, and scientific computing. The application should include a CV and 
suggestions of a research program and an area of interest and experience.

Further information
Please contact Ralf Nyholm, Ralf.Nyholm@maxlab.lu.se

Application 
The closing date for applications is February 1, 2010.
Send your application, marked 'PostDoc application', to:
MAX-lab 
Lund University
PO Box 118
SE-221 00 Lund
Sweden
or administration@maxlab.lu.se.




Two bioinformatics associate professorships available at BiRC, Aarhus University, Denmark

Date posted: 25 January, 2010

Deadline for applications: 1 March, 2010

Announcement will be removed: 2 March, 2010

Two positions as Associate Professor in bioinformatics are available starting September 1, 2010, at the Bioinformatics 
Research Center (BiRC), Aarhus University, Denmark. BiRC (http://www.birc.au.dk) is an interdisciplinary research center 
that employs about 35 researchers and PhD students.

The full annoucement of the two positions

* Associate Professor in Bioinformatics (informatics)
* Associate Professor in Bioinformatics (statistics)

including details about formalities and salary range, can be found via the list of available acadamic positions at:

http://science.au.dk/en/positions-and-fellowships/academic-positions/

Applications must be submitted online before March 1, 2010, according to the details in the full annoucment of the positions. 
For more information please contact the director of BIRC, Christian Nargaard Storm Pedersen, phone +45 8942 3121, 
e-mail: cstorm@birc.au.dk.


Ass Prof Systems Biology/ Intracellular Biophysics Uppsala

Date posted: 25 January, 2010

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

An assistant professorship in molecular systems biology is available
at Uppsala University:

http://www.personalavd.uu.se/ledigaplatser/3303forass_eng.html

Applicants with experience in experimental biophysics with
applications in living cells, including single molecule techniques and
advanced optical imaging, or development of corresponding
computational and theoretical methods for analysis of intracellular
reaction kinetics are particularly encouraged to apply.


Johan Elf
Program for Computational and Systems Biology, Uppsala University
Phone:+46 18 4714678
URL: http://www.icm.uu.se/molbio/elflab


Postdoctoral Position at EMBL, Hamburg

Date posted: 25 January, 2010

Deadline for applications: 31 January, 2010

Announcement will be removed: 1 February, 2010

The Meijers group at the EMBL Unit in Hamburg, Germany is looking for an outstanding post-doctoral scientist to work on structural aspects 
of the assembly and organization of the immunological synapse. We use a range of methodologies including cell biology, protein biochemistry, 
protein engineering, X-ray crystallography and bioinformatics to study the weak and specific interactions within the immunological synapse. 
The laboratory has access to state of the art protein production and characterization facilities. It will form an integral part of the new 
PETRA3 facility which is a new source of highly brilliant synchrotron radiation. Further information on the research performed in the lab 
can be found at:

http://www.embl-hamburg.de/research/unit/meijers/index.html

The ideal candidate should have a PhD in biochemistry or cell biology and extensive experience in protein expression and purification. 
Previous experience in protein structure determination would be an advantage. The candidate should have a willingness to develop new 
techniques in protein engineering that will open new avenues to study the dynamics and signaling of cell surface receptors.

An initial contract of 2 years will be offered to the successful candidate. This can be renewed depending on the circumstances at the 
time of review.

Closing date:  31st of January 2010

The European Molecular Biology Laboratory (EMBL) is an inclusive, equal opportunity employer offering attractive conditions and benefits 
appropriate to an international research organisation.

To apply please email a detailed CV, a statement of research interests and names (incl. e-mail address) of three potential referees 
by email quoting ref. no. W/09/PD/0103 in the subject line, to: application@embl.de.

General enquiries may be sent to jobs@embl.de


Senior Lecturer in Bioinformatics

Date posted: 25 January, 2010

Deadline for applications: 1 March, 2010

Announcement will be removed: 2 March, 2010

SciLifeLab Stockholm
Senior Lecturer in Bioinformatics

Science for Life Laboratory (SciLifeLab) is a national resource center for
large-scale biological research with focus on biomedicine, including genome
and proteome profiling, bioimaging, and bioinformatics. SciLifeLab
Stockholm has been established jointly by the Royal Institute of Technology,
Karolinska Institutet and Stockholm University. The main activities will be
concentrated in new buildings close to Karolinska Institutet and the
Karolinska University Hospital in Solna, near down-town Stockholm.
We are inviting applications for a Senior Lectureship in Bioinformatics at
SciLifeLab. The position is targeted to the areas genomics and/or systems
biology. The position will be placed at SciLifeLab, with employment at the
Department of Biochemistry and Biophysics, Stockholm University. The main
tasks will be research, research supervision, and scientific/administrative
responsibility for bioinformatics analysis at SciLifeLab.

For further information about the position and about SciLifeLab, please
contact Prof. Gunnar von Heijne (gunnar@dbb.su.se) or check the homepage
www.scilifelab.se. For a detailed announcement, see
www.su.se/english/about/vacancies

The application should include:
Letter of application, curriculum vitae, a list of the 10 most important
research publications, and a declaration of intent/vision within the framework
of the employment.

Descriptions of the candidates’ scientific, teaching and administrative
expertise, management experience, and expertise in working with the
community and in research and development information.

A personal assessment, a copy of the certificate of the most advanced degree,
and a complete list of publications.

Detailed guidelines for the application are found at
http://www.su.se/nyanstallning

The application (in a single PDF file) should be sent as an e-mail attachment
to registrator@su.se or as a signed application letter to Stockholm
University, The Registrar, SE-106 91 Stockholm, Sweden and should
arrive by March 1, 2010. Mark the application with the registration number
SU-612-2606-09.


Postdoctoral position available

Date posted: 25 January, 2010

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

PhD position at Structural Biology Brussels, Belgium

We are looking for a highly motivated PhD student interested in biochemical
and structural studies on tRNA modifying enzymes and enzyme complexes at
The Structural Biology Brussels laboratory (Vrije Universiteit Brussel / VIB) ?
Brussels, Belgium.

VIB (the Flanders Institute for Biotechnology) is an interdisciplinary non-profit
research institute based at 4 Flemish universities and employs a vibrant
community of 1000 life scientists. The Structural Biology Brussels lab focuses
on the functioning of proteins in all its aspects. Our multidisciplinary team of
about 40 researchers is housed in new laboratory facilities and combines
extensive expertise in structural biology (X-ray crystallography, NMR and
atomic force microscopy), biophysics and molecular biology (for more info:
http://www.structuralbiology.be/).

Project description: One of the topics in our lab deals with the study of the
structure and function of tRNA modifying enzymes. tRNA molecules are
transcribed as precursors that need to be extensively processed and
chemically modified before they can be used in translation. Many bases in
tRNA undergo post-transcriptional modification to increase the stability, to
modify cognate codon recognition and to affect aminoacylation properties.
Many of these post-transcriptional modifications are critical for proper tRNA
function. During your PhD you will be studying the functioning of tRNA
modifying enzyme complexes and the interaction with their tRNA substrates,
using an integrated approach of X-ray crystallography, enzyme kinetics and
different biophysical methods.

Start date: The position is available immediately and will remain vacant until a
suitable candidate is found.

Profile: Candidates should have a recent Masters degree in Biochemistry, Bio-
engineering, Biology, Chemistry or related. Skills in either molecular biology or
protein chemistry & purification or protein crystallography would be an asset.

Contact: Please send applications (including CV, research experience, and at
least two names and contact information for references) to:
Wim Versees, Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2,
1050 Brussel, Belgium - Wim.Versees@vub.ac.be.


Postdoctoral position available

Date posted: 25 January, 2010

Deadline for applications: unknown

Announcement will be removed: 5 April, 2010

Scientist position at Constellation pharmaceuticals

Scientist Structural Biology
Constellation Pharmaceuticals is a rapidly growing biopharmaceutical company dedicated to the development of novel therapeutics in the 
emerging field of Epigenetics.
The structural biology group at Constellation is looking for an enthusiastic and collaborative scientist to contribute to our drug 
discovery efforts.
This position will be part of an expanding structural biology group, with responsibilities  including (but not limited to) conducting 
laboratory experiments related to all aspects of crystallography from crystal growth to structure solution, analyzing, and interpreting 
scientific data, collaborating with other scientists, and performing computer-assisted structure based drug design.
The successful candidate will have a background in chemistry and an in-depth understanding of target/ligand interactions.   2-5 years 
of post-doctoral experience is required, and industrial experience (in pharmaceutical or biotech) is a plus.  A strong commitment to 
communicate structural information to colleagues in chemistry, enzymology and biology is expected.


Interested Candidates should forward their CV to careers@constellationpharma.com


Postdoctoral position available

Date posted: 25 January, 2010

Deadline for applications: unknown

Announcement will be removed: 16 March, 2010

Postdoctoral positions in Bioinformatics and Computational
    Biology (University of Michigan)

Highly motivated and creative postdoctoral candidates are sought to work at
the Center for Computational Medicine & Bioinformatics, University of Michigan
Medical School. The candidates will work on developing algorithms for protein
structure prediction, structure modeling of membrane proteins (especially G
protein-coupled receptors), protein-ligand docking, and new drug design.

Candidates with experience in one of following areas are encouraged to apply:

1) Protein folding and protein structure prediction
2) Monte Carlo and/or molecular dynamics simulations
3) GPCR and membrane protein modeling
4) Protein-protein & protein-ligand docking
5) Ligand screening and drug design

Strong candidates with interest and background in other related areas are also
considered. Ability in skillful writing scientific articles is required.

To apply, please send your CV, a brief description of your research background
and interest to Dr. Yang Zhang (Email: zhng@umich.edu), Center for
Computational Medicine & Bioinformatics, the University of Michigan, 100
Washtenaw Avenue, Ann Arbor, MI 48109-2218, USA.


Postdoctoral positions available

Date posted: 25 January, 2009

Deadline for applications: unknown

Announcement will be removed: 5 April, 2010

Postdoctoral positions available in the Protein Expression and X-ray Crystallography of National Cancer Institute

The Macromolecular Crystallography Laboratory (MCL), Center for Cancer Research (CCR), National Cancer Institute (NCI), National 
Institutes of Health (NIH) is seeking applications for postdoctoral fellowships from exceptional candidates for 2 of their Sections 
of the MCL. Dr. Jacek Lubkowski is seeking a candidate with a recent Ph.D. degree and a strong publication record in the areas of 
gene cloning, protein expression in eukaryotic systems, and protein purification. Dr. Lubkowski's research focuses on the structural 
properties of Janus kinases, members of the TREM family of receptors, and defensins; and correlating these properties with biological 
functions. Dr. David S. Waugh is seeking either a candidate with similar qualifications who is interested in leading an effort to 
develop novel technology for the production of recombinant proteins in eukaryotic organisms or a candidate who is already an accomplished 
protein crystallographer and who wishes to continue working in this field while also learning cutting-edge techniques for the production 
of recombinant proteins and protein engineering. Dr. Waugh's research interests revolve around methods development for the production of 
recombinant proteins, X-ray crystallographic studies of virulence factors from potential agents of bioterrorism, and structure-assisted 
development of therapeutic agents for the treatment of cancer. MCL is equipped with state-of-the-art X-ray equipment and complete 
infrastructure for the preparation and characterization of functional recombinant proteins. Additional support is available from a broad 
range of core services. US citizenship is not required but proficiency in English is essential. Please submit curriculum vitae including 
contact information for three references via e-mail to Dr. Lubkowski (lubkowsj@mail.nih.gov) or Dr. Waugh 
(waughd@mail.nih.gov).

Salary is commensurate with research experience and accomplishments. With nationwide responsibility for improving the health and well 
being of all Americans, the Department of Health and Human Services oversees the biomedical research programs of the National 
Institutes of Health.




Crystallography position at CSIRO, Melbourne

Date posted: 10 December, 2009

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

An opportunity is available immediately for a Research Scientist in x-ray
crystallography at the CSIRO Molecular and Health Technologies division.
Applications are accepted through the CSIRO employment website:

https://recruitment.csiro.au/asp/job_details.asp?RefNo=2009%2F966

(the job reference number is 2009/966)

International applicants are welcome and encouraged.

Part of the advertisement and a blurb on CSIRO is copied below, but more
information on CSIRO can be obtained on the following web site:
http://www.csiro.au/

And more specifically the CMHT division:
http://www.csiro.au/org/CMHT.html

Questions can be directed to me (Tom Peat) at the following email address:
tom.peat@csiro.au

We seek an enthusiastic and highly motivated protein crystallographer to
join the Structural Biology research group in Parkville. You will be
responsible for protein structure determination and structure-function
studies. You will work in a team and will liaise with other CSIRO divisions
and external collaborators to carry out their structural biology
requirements. You must have an interest in automation and high throughput
methodology. You will have a PhD or equivalent qualification with
postdoctoral research experience in protein crystallography.

You will be able to operate independently, but will enjoy working in a team
environment. You will develop your own research projects as well as liaising
with collaborators both within and outside CSIRO.  Your interests are
predominately protein structure-function studies, including structure-based
drug design. You will have a strong commitment to safe laboratory practice
and abide by OHS&E regulations.

The Commonwealth Scientific and Industrial Research Organisation is
Australia's national science agency and one of the largest and most diverse
research agencies in the world.  At CSIRO Molecular and Health Technologies
our scientists work in partnership to address key challenges in health and
in a range of industries requiring smart materials. Talented scientists are
undertaking biotechnology and advanced materials research drawing on a long
history of chemistry and molecular, cellular and structural biology to
develop and grow their capabilities. We form strong collaborative
relationships with industry, universities, Cooperative Research Centres
(CRCs) and research institutions to deliver leading edge research. Our
vision is to transform industries and improve health and wellbeing by
delivering creative molecular technologies.


Position available with Rigaku

Date posted: 10 December, 2009

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

Position available with Rigaku - Application Scientist in Life Sciences Division - The Woodlands, TX USA

Rigaku has an immediate opening for a motivated application scientist to
join the Life Sciences group in our North American headquarters, located
in The Woodlands, TX.

Since its inception in Japan in 1951, Rigaku has been at the forefront of
analytical and industrial instrumentation technology. With hundreds of
major innovations to its credit, Rigaku and its subsidiary companies are
world leaders in the fields of protein X-ray crystallography, automation,
cryogenics and X-ray optics. Rigaku offers a rewarding work environment
and excellent benefits. The successful candidate will join the world?s
leading provider of analytical X-ray equipment, assist in development and
implementation of software improvements, and lead software and hardware
demonstration/training sessions in support of both pre-sales and
post-sales activities.

The candidate must have a PhD degree in a relevant field and have previous
experience in protein crystallography. Candidates must have excellent oral
and written communication skills, must be able to manage projects and
deadlines effectively and should possess both a strong customer service
ethic and strong technical troubleshooting skills. Additionally,
candidates must be prepared and able to travel without restriction to
X-ray facilities throughout North America, with possibility for
international travel. Fluent English is required but does not need to be
your first language. Preference will be given to scientists with hands-on
experience in the use and maintenance of X-ray systems, familiarity with
high-throughput automated systems, experience with teaching and a high
level of aptitude in X-ray instrumentation and diffraction methods.

Please send resumes by mail to Rigaku Americas, 9009 New Trails Dr., The
Woodlands, TX 77381-5209, Attention: Human Resources, by fax to +1
281-364-3628 or by email to resumes@rigaku.com.
Rigaku offers a rewarding work environment and excellent benefits. All
applicants are kept in strict confidence. Benefits package including
Health, Dental, Vision, STD, LTD, Life insurance, section 125 flexible
spending accounts, a 401(k) plan and more. Rigaku is an EEO/AA Employer
M/F/D/V. Applicants must be able to prove they can legally work in the US.

For more information, please visit the job listing at
http://www.rigaku.com/jobs.html#app-sci


Postdoctoral position available

Date posted: 10 December, 2009

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

Postdoctoral Fellow position

An opportunity is available immediately for postdoctoral research with
Drs. P. Howard and P. Grochulski as part of the Molecular Design
Research Group at the University of Saskatchewan.  This is a multi-year
funded position for structure and function studies on the type II
secretion system utilized by many bacterial pathogens in the secretion
of protein toxins.  The successful candidate will have documented
experience in protein structure determination, including 1) protein
purification and crystallization, 2) data collection and processing, 3)
structure determination and model refinement.  Modern protein
purification and analysis facilities as well as the Canadian Light
Source will provide a highly motivated individual with an excellent
foundation for career development in structural biology.   Interested
candidates should apply with a cover letter and C.V. to Dr P. Howard at
peter.howard@usask.ca or to Dr P. Grochulski at
pawel.grochulski@lightsource.ca


Postdoctoral position available

Date posted: 10 December, 2009

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

Postdoctoral Positions Available in Structural Biophysics and Protein Engineering in Rockville, Maryland, USA

Two NIH funded postdoctoral position are available for highly motivated individuals at the
Center for the Advanced Research in Biotechnology (CARB) at the University of Maryland
Biotechnology Institute in Rockville, Maryland, USA.  Several research projects are available
to study the interleukin-7 signaling pathway at the structural, biochemical, and biophysical
levels.  Candidates must have a Ph.D. degree in biochemistry or a related field, with
experience in molecular biology, bacterial and insect cell protein expression and
purification.  Prior experience in structural (X-ray crystallography or NMR spectroscopy) and
biophysical techniques is preferred.  Salary will be commensurate upon experience.  For
further information or to apply for the positions please send a cover letter, CV, and two
references to Dr. Scott Walsh (email: walshs@umbi.umd.edu).


Computational Systems Biology Postdoctoral Position

Date posted: 10 December, 2009

Deadline for applications: unknown

Announcement will be removed: 10 March, 2010

Computational Systems Biology Postdoctoral Position - 
Center for the Study of Systems Biology at the Georgia Institute of Technology

Outstanding Postdoctoral applicants are sought in Computational Systems Biologyto work with Professor Jeffrey Skolnick at the 
Center for the Study of SystemsBiology at the Georgia Institute of Technology in the following areas:

  • Proteome scale virtual ligand screening
  • Development of algorithms to minimize drug side effects
  • Development of algorithms to predict metabolites with anticancerproperties
  • Structure prediction of GPCRs followed by virtual ligand screening
  • Prediction of protein-protein and protein-DNA interactions
  • Development of algorithms for protein structure refinement
  • Development of multiscale modeling approaches for the simulation ofvirtual cells Highly creative, outstanding individuals are sought with the followingqualifications:
  • Extensive experience in developing computer code in languages such asFortran, C, C++, and/or Perl.
  • Previous experience doing international quality research in structuralmodeling, virtual ligand screening, bioinformatics, or computational genomicswould be major advantages.
  • A track record of publication in high quality international journals.
  • Ability to work in a team, yet think independently. To apply please send your CV to: skolnick@gatech.edu.

  • Postdoctoral position in Protein Crystallography, Sydney

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    A postdoctoral position is available in the Protein Structure Group at the University of New South Wales, Sydney, Australia. 
    The focus of the project is the TGF-beta superfamily cytokine, MIC-1 (Johnen et al., Nat Med. 2007 13:1333-40). This is part 
    of an integrated research program in collaboration with the Centre for Applied Medical Research at St Vincent?s Hospital Sydney, 
    where MIC-1 was discovered. The candidate should have a strong background in protein crystallography with skills in molecular 
    biology, protein chemistry and molecular modelling desirable.
    
    The postdoc will be based at UNSW where we have in house facilities for molecular biology, protein expression, purification 
    and characterisation. We have a robotic crystallisation suite comprising a Hamilton Starlet 8 channel fluid handling system, 
    a Phoenix nanodrop crystallisation robot and a CrystalPro HT110 visualisation system with 100 plate hotel. Data collection 
    facilities include a Rigaku MicroMax007 rotating anode generator equipped with a MAR34 detector, Osmic mirrors and Oxford 
    cryo system. We have regular access to synchrotron sources.
    
    The position is funded for three years.
    
    For further information contact (preferably by email):
    
    Paul Curmi
    School of Physics, University of New South Wales
    Sydney, Australia
    Email p.curmi@unsw.edu.au
    URL: www.phys.unsw.edu.au/~pmgc
    
    


    Research associate

    Date posted: 10 December, 2009

    Deadline for applications: 19 February, 2010

    Announcement will be removed: 20 February, 2010

    RESEARCH ASSOCIATE  (REF: 2989)
    SCHOOL OF BIOMEDICAL, BIOMOLECULAR AND CHEMICAL SCIENCES
    
    Structural Biology of Molecular Targets from Helicobacter pylori
    
    21 month appointment
    Salary range:  Level A $53,542 - $72,537 p.a. - minimum startingsalary for appointee with PhD will be $70,058 p.a.
    Closing date:  Friday, 19 February 2010
    
    The School is undertaking research aimed at elucidating the structural and functional mechanisms of molecular targets from 
    Helicobacter pylori, involved in immune evasion by the organism.  The project is highly cross disciplinary in nature involving 
    crystallographic studies carried out in the Vrielink Laboratory, organic chemistry synthesis and inhibitor design in the Stubbs
    Laboratory and in vivo functional studies in the group of Nobel Laureate Professor Barry Marshall.  The overarching aim of this 
    project is to design inhibitors of key target enzymes that can be used as novel therapeutic agentsto treat H.pylori infections.
    
    A postdoctoral position is available to pursue crystallographic studies of the target proteins.  The position will involve 
    developing protein expression and purification protocols followed by downstream crystallographic studies. Applicants must have 
    a PhD or equivalent in Biochemistry or a relateddiscipline and with experience at macromolecular crystallography.  A strong
    background in molecular biology, protein expression and purification would behighly advantageous. The appointee will carry out 
    research in the Vrielink laboratory but will also be part of a multidisciplinary team within the School of Biomedical, Biomolecular 
    and Chemical Sciences involving chemists and microbiologists with outstanding expertise at the study of H.pylori.  As such this 
    position offers excellent opportunities to interact across multiple disciplines and hence extend research expertise and career 
    development.
    
    The Structural Biology Laboratory at the University has outstanding facilities for protein expression and purification as well 
    as in-house X-ray facilities including a rotating anode generator and two MAR Imaging plate detectors. Crystallization robots 
    are also available or crystallization experiments.  Highresolution X-ray data collection will be carried out at the 
    Australian Synchrotron.
    
    Perth is a thriving and vibrant city, which lies along the Indian Ocean and benefits from outstanding natural beauty and 
    many opportunities for outdoor activities.  Benefits include superannuation and salary packaging opportunities.  Some 
    assistance with relocation expenses may be negotiated.
    
    For further information regarding the position please contact Alice Vrielink byemail alice.vrielink@uwa.edu.au.
    
    * PLEASE NOTE: The University will be closed from Friday 25 December 2009 until Tuesday 5 January 2010.
    
    APPLICATION DETAILS: For copies of the position description please access thewebsite http://jobs.uwa.edu.au/.  
    
    Written applications quoting the reference number, personal contact details, qualifications and experience, along with 
    contact details of three referees should be sent to Director, Human Resources, The University of Western Australia, 
    M350, 35 Stirling Highway, Crawley WA 6009or emailed to jobs@uwa.edu.au by the closing date. 
    


    Postdoctoral position available

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    postdoc position in Cambridge
    
    A Medical Research Council funded post doctoral position is available to work with Dr Matt Higgins in the Cambridge University 
    Department of Biochemistry on the structural biology and biochemistry of malarial cell surface proteins. This will involve the 
    production and characterisation of malarial proteins, the development of interaction assays and structural analysis by protein 
    crystallography and nuclear magnetic resonance spectroscopy. Experience in NMR and/or crystallography would be of great benefit. 
    This post will be available for up to 36 months in the first instance and will start early in 2010.
    
    Applications should include a covering letter describing relevant research
    experience to date, a CV, completed PD18 form (Part 1 and 3) (The form PD 18 can
    be downloaded from http://www.admin.cam.ac.uk/offices/personnel/forms/pd18) and
    the names and addresses of two referees. These should be sent quoting the
    reference PH06012 by email by 18th December 2009 to jobs@bioc.cam.ac.uk or post to 
    The Personnel Secretary, 
    Department of Biochemistry, 
    Building O, 
    Downing Site, 
    Tennis Court Road, 
    Cambridge, UK, CB2 1QW.
    
    * Limit of tenure: 36 months
    


    Structural Biologist - permanent position in Central London

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    Structural Biologist - permanent position
    Central London, UK
    
    Cancer Research Technology (CRT) is a specialist oncology company which
    advances discoveries arising from Cancer Research UK and other
    prestigious oncology focused organizations into potential therapies for
    the benefit of cancer patients.
    
    CRT is seeking to recruit a highly motivated protein scientist /
    structural biologist to join our X-ray structure determination team.
    The team has access to state-of-the-art data collection and
    crystallization facilities within the School of Crystallography,
    Birkbeck College, London and is adjacent to CRT's Discovery Laboratories
    within the Wolfson Institute of Biomedical Research, University College
    London.
    
    The successful candidate should have experience in one or more of the following areas:
    - Production and characterization of crystallization-grade protein for structural analysis
    - Crystallization screening and optimization of protein-ligand complexes
    - X-ray data collection and structure determination
    
    You should ideally be qualified to PhD level or equivalent. In addition,
    you will possess excellent communication and organisation skills, and
    will be able to contribute positively to interactive collaborations
    within CRT, Cancer Research UK laboratories and other external
    organisations.  Previous involvement in projects relating to oncology
    and experience within a pharmaceutical environment would be desirable.
    
    This is a permanent position with significant opportunity to influence
    the development of new cancer therapeutics and will suit a highly
    talented individual with strong interpersonal skills.
    
    Please note that applications will only be accepted from candidates who
    have proof of their right to work in the U.K.
    
    To apply, please send a copy of your CV and a covering letter, quoting
    the reference number XR1209, to the Head of Medicinal Chemistry by email
    to crtrecruitment@CancerTechnology.com
    


    Postdoctoral position available

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    Post-Doctoral position
    
    An opening for a Post-doctoral position is available starting January 15th in the Structural Basis of Genome Integrity 
    Group at the Spanish National Cancer Research Centre in Madrid (CNIO).
    
    The ideal candidate should have a PhD in structural biology, biochemistry or a related field and should have experience 
    in molecular biology, protein expression and purification. Additional experience in macromolecular X-ray crystallography 
    and/or single-particle electron microscopy is highly desirable. Experience with protein expression in eukaryotic systems 
    is an advantage. Fluency in English required.
    
    The research focuses on structural and functional aspects of genome integrity, with particular emphasis on employing 
    X-ray crystallography and single-particle electron microscopy to elucidate the structures and understand the function 
    of large macromolecular complexes involved in DNA recombination and repair.
    
    The candidate will work with a team of highly motivated structural biologists and biochemists and collaborate with 
    cell biology and computational groups at the CNIO. The Structural Basis of Genome Integrity Group is a newly established 
    research group led by Dr. Santiago Ramon-Maiques who recently moved to the CNIO from the Institute of Biomedicine of 
    Valencia, and previously worked in the group of Dr. Wei Yang at the National Institutes of Health, in Bethesda.
    
    We offer: 
  • An appointment for a period of one year with the possibility of extension up to five years.
  • A competitive salary and an attractive benefits package.
  • Access to state-of-the-art facilities for X-ray crystallography and electron microscopy.
  • The opportunity to be part of a European Cancer Research Centre of excellence that successfully combines basic and applied research. Applications can be sent at any time, preferably before 1st of January 2010. Applicants should submit a CV, a statement of research interests, and the names and contact information of two references to Santiago Ramon-Maiques (sramon@ibv.csic.es). All enquiries and applications will be treated confidentially.

  • Postdoctoral position in anesthetic discovery

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    We seek a structurally-oriented post-doctoral fellow to participate in a general anesthetic discovery program consisting 
    of high through-put approaches, coupled to medium through-put secondary screens, to include x-ray crystallography, 
    isothermal titration calorimetry and in vivo assays.  This project is funded by NIH and represents a collaboration 
    between the University of Pennsylvania Department of Anesthesiology & Critical Care, Drexel University Department 
    of Biochemistry and Molecular Biology and the National Chemical Genomics Center.  The successful candidate will 
    have a Ph.D., M.D., or both, with training biochemistry, biophysics and/or structural biology. Successful candidates 
    will be able to work independently but will also have excellent collaborative skills.  Please contact Rod Eckenhoff 
    at Roderic.eckenhoff@uphs.upenn.edu, or Pat Loll at ploll@drexelmed.edu.
    
    


    Postdoctoral position in DUB structural biology

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    A postdoctoral position is available to study the structures and functions of a novel class of human deubiquitinating 
    enzymes involved in neurodegeneration.
    
    An NIH-funded position is available immediately to study the structure, catalytic function, and ligand-binding 
    properties of the human Josephin domain-containing proteins. These proteins include ataxin-3, a polyglutamine 
    protein that is the causative agent of Machado-Joseph disease, the most common inherited ataxia. Well-diffracting 
    crystals are in hand for  several protein-substrate complexes. We seek a talented protein chemist/structural 
    biologist to assist in studies of  these interesting and important molecules. Experience in X-ray crystallography 
    is a plus, but we are also happy to entertain applications from biochemists/biophysicists who seek to extend their 
    training to diffraction analysis.
    
    Drexel University has been ranked among the top 50 private universities in the United States, and its College of 
    Medicine is the largest private medical school in the nation. The Department of Biochemistry & Molecular Biology 
    offers a stimulating and supportive environment for biomedical research. The department is located in the heart 
    of downtown Philadelphia, which is a cosmopolitan and highly livable city.
    Please direct inquiries to Pat Loll: pat.loll@drexel.edu.
    


    Positions available at PDBeurope

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    - Software Engineer/Scientific Programmer - to work on database
    integration and the development of new ways to access and use the
    structural archive:
    http://www.embl.de/aboutus/jobs/jobs_embl_ebi_hinxton/2010/w_09_095_ebi/
    index.html
    (contact: Sameer Velankar - sameer@ebi.ac.uk)
    
    - Scientific Programmer Electron Microscopy - to work on developing new
    tools for the EM field (as part of the EM Data Bank, EMDB):
    http://www.embl.de/aboutus/jobs/jobs_embl_ebi_hinxton/2010/w_09_109_ebi/
    index.html
    (contact: Christoph Best - best@ebi.ac.uk)
    
    Two other positions are also still open:
    
    - Database Engineer (closes on Monday!):
    http://www.embl.de/aboutus/jobs/jobs_embl_ebi_hinxton/2009/w_09_078_ebi/
    index.html
    (contact: Tom Oldfield - oldfield@ebi.ac.uk)
    
    - NMR Project Leader - a great opportunity for a talented and ambitious
    young NMR-ist to help define how NMR structural data is validated,
    represented and served back to the wider biological community:
    http://www.embl.de/aboutus/jobs/jobs_embl_ebi_hinxton/2009/w_09_077_ebi/
    index.html
    (contact: Wim Vranken - wim@ebi.ac.uk)
    


    PhD student positions available

    Date posted: 10 December, 2009

    Deadline for applications: 21 February, 2010

    Announcement will be removed: 22 February, 2010

    PhD Fellowships in Computational Biology and Scientific Computing
    
    The International Max Planck Research School for Computational Biology and Scientific Computing,
    
    a joint graduate program of the Freie Universitaet Berlin and the Max Planck Institute for Molecular Genetics, Berlin,
    invites applications for a PhD program.
    
    The PhD program is open for international students holding a Master (or equivalent) degree in bioinformatics, computer science, 
    physics, mathematics, or biology.
    
    The closing date for applications is February 21, 2010.
    
    We would be grateful if you could communicate the announcement to interested students. 
    A poster can be downloaded from http://www.imprs-cbsc.mpg.de/download/poster2010.pdf
    
    For further details and the application procedure, please visit http://www.imprs-cbsc.mpg.de
    


    Sales Engineer position available

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    Position available - Rigaku EuropeSales - Life Sciences Division - Sales Engineer
    
    Sales Engineer - Rigaku Europe - Life Sciences Division
    We are recruiting an additional Sales Engineer for our European Life
    Sciences Division.  For full details, please see the jobs listing on the
    Rigaku website:
    http://www.rigaku.com/jobs.html#sales-eu
    


    Technical Key Account Managers in Europe and US

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    Microlytic is hiring Technical Key Account Managers
    
    To meet increasing customer demand Microlytic is hiring individuals with a
    strong scientific background for serving our growing base of large academic
    and pharmaceutical accounts in Europe and US. The technical key account
    managers will be traveling to customer sites to give seminars about
    Microlytic's products and applications, facilitate integration of products
    within customer workflow, and solve technical issues with customers.
    
    
    Job description
    
    The candidates will be working in a start up environment where individuals
    have many responsibilities and will be expected to help out in a variety of
    areas.  However, the primary focus of these positions is serving key
    accounts, specifically responding to customer requests, assisting customers
    with product integration, providing technical support and managing sales.
    Additionally, the candidates will be responsible for organizing trade shows,
    setting up workshops, preparing application notes and other technical
    documents. Finally candidates are encouraged to participate in product
    development.
    
    Candidates should expect significant travel activity, since they will be
    serving accounts that are geographically distributed within US and Europe.
    
    Qualifications
    
    The ideal candidates will have some or all of the attributes listed below
    
    -          PhD in biological, chemical or physical sciences - preferably in protein crystallography
    -          Solid scientific understanding of protein crystallography
    -          Very good communication and presentation skills
    -          Willing to perform significant travel
    
    Previous experience should include at least one of the following:
    
    -          Sales experience, from  life science tools industry, serving large academic and industrial accounts
    -          Technical support experience within the life science tools business
    -          Working as protein crystallographer in a large lab or industrial group
    
    Interested candidates may submit resume and cover letter via email to:
    
    Morten Sommer, ms@microlytic.com
    


    Post-Doctoral Position in Structural Biology - Imperial College London

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    Postdoctoral/Research Associate in Structural Biology - Division of Molecular Biosciences - Imperial College - London
    
    Applications are invited for a Cancer Research UK funded Research Associate position investigating structure and mechanism of cell signalling systems 
    involved in ER stress.  The position will utilize biochemical and structural techniques, principally protein X-ray crystallography, to characterize 
    proteins and complexes involved in ER stress pathways.  The research will be based in the Division of Molecular Biosciences, under the supervision of 
    Dr Maruf Ali.
    
    The position will involve expression, purification and crystallization of recombinant protein obtained from both baculovirus and bacterial expression 
    systems. The role will also make use of biophysical and biochemical techniques for protein characterisation.
    
    The Division of Molecular Biosciences has access to state of the art facilities for all aspects of structural biology, including NMR, EM and X-ray m
    achines.
    
    The successful candidate will hold a PhD in structural biology (or close to completion) or the equivalent professional qualification and experience and have a track record of protein expression, purification and crystallisation, for structural analysis.
    
    The starting salary for the post will be in the range of ?26,720 - ?30,520 per annum. For further details including the job specifications please visit the college webpage http://www3.imperial.ac.uk/employment (NS2009168AB for Research Associate in Structural Biology).  The preferred method of application is also online via the college website.
    


    Vacancy for a graduate student in Barcelona

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    We have a vacancy for a Ph.D. student to work on molecular biology/biochemistry to start next
    Summer. I would greatly appreciate if you could pass the following link to interested candidates.
    Thank you very much,
    Xavier
    
    http://www.ibmb.csic.es/images/stories/Xavier_Gomis/pdf/becari_fpi_2010.pdf
    
    


    Postdoctoral positions at Cornell University, Ithaca, New York, USA

    Date posted: 10 December, 2009

    Deadline for applications: unknown

    Announcement will be removed: 10 March, 2010

    Postdoctoral positions at Cornell University, Ithaca, New York, USA
    
    A crystallography postdoctoral position in RNA Biology is available immediately in the lab of Prof. Ailong Ke at Cornell University, Ithaca, NY, USA. 
    Related research projects will employ integrated approaches to understand the structure and function of RNA and RNA-protein complexes. The lab is 
    interested in two main research areas: 1. structure and working mechanism of macromolecular machines in the eukaryotic RNA processing and degradation; 
    2. Structure and conformation dynamics of important RNA and RNA-protein complexes. Please check Nat Struct Mol Biol. 2008 Oct;15(10):1076-83, and Proc 
    Natl Acad Sci U S A. 2007 Oct 23;104(43):16844-9 for representative publications. The lab has extensive crystallographic resources, including regular 
    access to synchrotron beamlines at the Cornell High Energy Synchrotron Source (CHESS) on campus.
    
    Candidates should have (or expect) a Ph.D. or M.D. and should have experience in protein purification, crystallization, and structure determination.
    
    For additional information please see:
    http://sites.google.com/site/kelaboratory/
    
    To apply, please send CV and names of 3 references to:
    
    Ailong Ke
    Department of Molecular Biology and Genetics
    Cornell University
    Ithaca, NY, 14853
    ak425@cornell.edu 
    


    Postdoctoral position available

    Date posted: 21 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 21 February, 2010

    Postdoctoral positions at NIH, Research Triangle Park, North Carolina, USA
    
    Two postdoctoral positions are available in the Genome Stability Structural Biology group (Williams Laboratory) of 
    the National Institute of Environmental Health Sciences (NIEHS/NIH), Research Triangle Park, North Carolina.  Related 
    research projects will investigate structural and functional aspects of DNA repair and maintenance of genome integrity 
    using X-ray crystallography, small angle X-ray scattering (SAXS) and biochemical methods, with collaborative in vivo 
    analysis of targeted systems.
    
    The Williams group is in the Laboratory (i.e., department) of Structural Biology (LSB) in the Division of Intramural 
    Research, with investigators renowned for their contributions to the area of genome stability, protein-DNA, and 
    protein-RNA structural biology and biochemistry.  The exceptional training environment within the LSB is coupled to 
    the strong NIEHS/NIH infrastructure, and offers a highly supportive and interactive scientific environment with many 
    diverse areas of expertise.  The group has a fully equipped molecular biology and protein chemistry laboratory and access 
    to superb in house X-ray crystallographic data collection and crystallization robotics equipment.  NIEHS is located in an 
    especially attractive part of North Carolina that is central to prominent research institutions, and within driving distance 
    of the beautiful North Carolina coast to the East and the Appalachian mountains to the West.
    
    Applicants must possess a doctoral level degree.  While candidates with less than five years of relevant postdoctoral 
    research experience are eligible, recent graduates are encouraged to apply.  Experienced applicants with skills in 
    molecular biology, protein chemistry, and/or backgrounds in protein structure are preferred.  Motivated individuals 
    looking to expand their skill set to include crystallographic methods are also encouraged to apply.  Starting 
    postdoctoral salary is $46,800, plus medical benefits.
    
    For additional information please see:
    http://www.niehs.nih.gov/research/atniehs/labs/lsb/index.cfm 
    http://www.niehs.nih.gov/research/atniehs/labs/lsb/genome/index.cfm
    
    To apply, please visit:
    www.training.nih.gov/apps/publicForms/postdoctoral/forms/adIndex.aspx?strSearch
    Job ID: PD-4663
    
    Or send CV and names of 3 references to:
    
    R. Scott Williams
    Laboratory of Structural Biology
    NIH/NIEHS, Maildrop F3-03
    111 TW Alexander Dr
    RTP, NC 27709
    williamsrs@niehs.nih.gov
    
    The National Institute of Environmental Health Sciences (NIEHS) is located in Research Triangle Park, North Carolina. 
    The NIH is dedicated to building a diverse community in its training and employment programs.
    


    Postdoctoral position available

    Date posted: 21 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 21 February, 2010

    Postdoctoral Positions UCSF/Stroud Lab
    
    The Stroud Lab at UCSF (http://www.msg.ucsf.edu/stroud/index.htm) is looking to fill multiple post-doctoral positions in 
    1. membrane protein crystallography and 
    2. structure and function of RNA-modifying enzymes.
    
    Applicants should have background in biochemistry, molecular biology, and/or crystallography.
    
    The position in membrane proteins will be in close affiliation with MPEC (http://mpec.ucsf.edu/index.htm) and 
    CSMP (http://csmp.ucsf.edu/index.htm).  Candidates with experience with membrane proteins is highly preferred 
    for this position.
    
    If interested, please email your cover letter and CV to:
    
    betheil@msg.ucsf.edu
    
    Please specify the position that you are applying to.
    
    


    Postdoctoral Research Assistant at the Humboldt University Berlin, Germany

    Date posted: 12 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 12 February, 2010

    Postdoctoral Research Assistant at the Humboldt University Berlin, Germany
    
    The Humboldt-University Berlin (HU-Berlin) is looking for a
    Postdoctoral Research Assistant for Macromolecular Structure and
    Interaction to support the operation of the MX-beamlines located at the
    BESSY II storage ring (headed by Dr. Uwe M?ller, BESSY/HZB) and to
    conduct research at the HU-Berlin under the guidance of Prof. Dr. Holger Dobbek. 
    BESSY/HZB collaborates with the HU-Berlin in operating three state-of-the-art
    experimental stations for bio-macromolecular crystallography at one of
    the world's most modern synchrotron radiation sources for VUV and soft
    X-rays.
    
    Description:
    The successful candidate will support MX-beamline users in data
    collection and analysis, participate in the development, implementation
    and commissioning of MX-beamline instrumentation, and pursue his/her own
    research in the field of macromolecular structure and function of cofactor containing enzymes.
    
    Requirements:
    Applicants should hold a Ph.D. in either biological, chemical or physical
    sciences and have a strong background in all aspects of
    bio-macromolecular crystallography, in particular in the use of the
    relevant computer programs. The position also requires the documented
    ability to conduct independent research as well as excellent
    communication and interpersonal skills.
    
    Salary:
    The salary will be based on German Vgr. IIa- BAT-O nach AnwTV HU.
    
    Entry:
    The position is available immediately.
    
    Limitation:
    We are initially offering a three-year contract with the possibility of
    an extension.
    
    Disabled persons with same qualification are given preference.
    
    Applications under the reference number AN/147/09 should include a
    cover letter, curriculum vita, a publication list, and a detailed
    summary of research experience and interests.  Electronic submissions
    organized within a single pdf-file and inquiries may be addressed to:
    umue@bessy.de 


    Postdoctoral position available

    Date posted: 12 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 12 February, 2010

    Postdoctoral Fellow Position in Computational Structural Biology 
    at the Zhang Initiative Research Unit, Advanced Science Institute, RIKEN, Japan
    
    We are seeking a highly motivated and experienced computational structural biologist to join the Zhang Initiative 
    Research Unit at RIKEN. The successful candidate will use computational tools to tackle problems in the area of 
    protein crystallographic phasing or scaffold-based drug design.
    Qualifications: This position requires a PhD in biophysics, biochemistry, chemistry, bioinformatics or structural 
    biology with experience in employing computational tools to solve biological or chemical problems. Experience in 
    protein structure analysis, X-ray crystallographic method development or structure-based drug design are highly 
    desired. Proficiency in object-oriented programming and scripting languages are also required. Experience in high 
    performance computing, network computing or grid computing would be a plus. The ideal candidate should possess a 
    track record of accomplishments demonstrating technical proficiency, independent thinking, and scientific creativity. 
    The research environment in the unit is international and English will be used for communication and knowledge of 
    Japanese is not required.
    
    Salary and benefits: This is a full-time position with an annual renewable contract. Salary will be commensurate with 
    qualification and experience. Commuting and housing allowance will be provided.
    
    Application and required documents:
    Complete CV (including list of publications) and names and contact information of three references.
    
    Contact information:
    Dr. Kam Zhang
    Zhang Initiative Research Unit
    Advanced Science Institute
    RIKEN
    2-1 Hirosawa, Wako, Saitama 351-0198, Japan
    E-mail: zhang-unit@riken.jp
    


    Programmer for NE-CAT/APS

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 6 February, 2010

    Scientific Computer Manager at NE-CAT, Cornell University
    
    The Northeastern Collaborative Access Team (NE-CAT), located at the Advanced Photon Source at the Argonne 
    National Laboratory in Argonne, IL and managed by Cornell University, is seeking applicants for a Computer 
    Manager specializing in scientific programming. This is a one year position that has the potential to be 
    extended. The primary responsibility of the incumbent will be to participate in the development of software 
    for X-ray crystallographic data collection and processing. More specifically, projects under active 
    development include real time data monitoring and processing, strategy calculation for kappa goniometry, 
    scaling and merging of multiple crystals, continuous rastering of needle-like samples during data collection, 
    and user interface features that include a remote interface for monitoring the progress of data collection. 
    In addition to software development, the candidate will be responsible for management of the current beamline 
    computers and overseeing the implementation of a new 8-node cluster.
    
    Knowledge, Skills, and Experience Requirements
    
    Applicants should have a Bachelors degree in computer systems analysis, computer programming, engineering or 
    physical sciences or a related field, with a computer programming emphasis. The applicant should have a strong 
    interest in scientific programming. Working knowledge of advanced programming languages such as Python and C++ 
    as well as experience administering a Linux cluster are desirable assets as is prior experience with use of 
    crystallography software and analysis of data from synchrotron sources. Applicants must have strong 
    interpersonal skills in working closely and successfully with a diverse set of beamline users and other staff 
    members as well as good communication skills, both oral and written.
    
    For more information about NE-CAT, please see our website, http://necat.chem.cornell.edu. Candidates should 
    fill out an application at https://cornellu.taleo.net/careersection/10164/jobdetail.ftl?lang=en&job=11588. 
    Applications will be accepted until the position is filled. Cornell is an equal opportunity, affirmative action 
    educator and employer.
    


    Postdoct. and PhD stud. positions in Laval Univ., Canada

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 6 February, 2010

    Postdoctoral and Ph.D. positions are available at Laval University Hospital
    Research Center (CHUQ), for the study of structural biology, cell biology and
    function of important enzymes. Our research involves new projects in steroid
    enzyme structure-function and in estrogen synthesis pathways, supported by
    the  Canadian Institutes of Health Research (CIHR). Inhibitors of steroid
    enzymes will be searched for the treatment of breast cancer and will be
    tested in cells and animal models. Crystallography, cell biology and enzymology
    back grounds are highly welcome.
    
    Since the determination of the first human steroid enzyme structure, the type
    1  17beta-hydroxysteroid dehydrogenase, we have determined a series of
    enzyme structures, resulting in leads for the cancer therapy. Expertise in
    crystallizing membrane and hydrophobic proteins, cell biology and enzymology
    are available in the laboratory with state-of-the-art facilities. Quebec City,
    with its original European style, is alongside the St. Laurence river, providing a
    beautiful and an excellent research environment. All positions will be well
    remunerated at CIHR levels, while the living expenses are modest in Quebec
    City.
    
    For those who are interested in the above projects, please send your C.V. to
    sxlin@crchul.ulaval.ca 


    Postdoc Position in Electron Microscopy Birkbeck University of London

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 31 January, 2010

    Postdoc Position in Electron Microscopy  Birkbeck University of London
    
    Two postdoctoral positions are available in the group of Professor Helen
    Saibil, in the EM lab, Crystallography Department, Birkbeck College,
    London. The posts are funded by a Wellcome Trust Programme grant in the
    field of protein quality control, and will involve cryo EM studies on
    chaperone-substrate interactions and on cellular aggregates, using both
    single particle and tomography methods. The Birkbeck EM lab is well
    equipped with a 300 kV Polara microscope, a 200 kV FEG system, and 120
    kV and 100 kV cryo microscopes, as well as sample preparation equipment
    for single particles, high pressure freezing, vitrified sections and
    freeze substitution.
    For further information, please see
    http://people.cryst.bbk.ac.uk/~ubcg16z
    


    Postdoctoral position available

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 2 February, 2010

    Position at Med Univ Innsbruck
    
    The Division of Human Genetics/Clinical Genetics,
    Innsbruck Medical University, seeks to appoint a Group Leader
    in Mitochondrial Protein Research for the expansion of a research
    focus on the analysis of protein function and interaction in the
    pathogenesis of inherited mitochondrial disorders.
    
    http://www.ruppweb.org/Humgen-Innsbruck.pdf
    
    Although not specifically mentioned, there interest in the structural basis of these disorders.
    
    


    Postdoctoral position available

    Date posted: 6 November, 2009

    Deadline for applications: 29 January, 2010

    Announcement will be removed: 30 January, 2010

    Post-doctoral position. Structural Biology Research Center, Tsukuba, Japan
    
    [Closing date]
    All documents should arrive at the latest on the 29th of January 2010.
    
    [Job description]
    The Structural Biology Research Center offers a state of the art international and stimulating environment 
    for research in a multi-disciplinary framework. Notably, molecular structural biology research in the field 
    of intracellular transport and posttranslational modification including ubiquitylation is vigorously pursued 
    and tightly linked with development and operation of synchrotron protein crystallography beamlines at the 
    Photon Factory. We are looking for an enthusiastic post-doctoral fellow to work on proteins involved in 
    intracellular transport and posttranslational modification processes. Some of the recent publications on 
    the relevant research areas include:
    
    *Rahighi S, Ikeda F, Kawasaki M et al. (2009) Specific recognition of linear ubiquitin chains by NEMO is 
    important for NF-kappaB activation. Cell 136:1098-1109
    
    *Dikic I, Wakatsuki S, Walters KJ (2009) Ubiquitin-binding domains - from structures to functions. Nat Rev 
    Mol Cell Biol 10:659-671
    
    *Chavas LM, Ihara K, Kawasaki M et al (2008) Elucidation of Rab27 recruitment by its effectors: structure 
    of Rab27a bound to Exophilin4/Slp2-a. Structure. 16:1468-77
    
    *Kudo N, Kimagai K, Tomishige N et al. (2008) Structural basis for specific lipid recognition by CERT 
    responsible for nonvesicular trafficking of ceramide. Proc Natl Acad Sci U S A. 105:488-93
    
    *Hirano S, Suzuki N, Slagsvold T et al. (2006) Structural basis of ubiquitin recognition by mammalian 
    Eap45 GLUE domain. Nat Struc Mol Biol. 13:1031-2
    
    More information can be obtained on the following website: http://pfweis.kek.jp/eng/index.html.
    
    [Qualifications and Experience]
    Motivated applicants should have a Ph.D. in a relevant field. Working experience in molecular biology and 
    biochemistry is required. Previous experience with large-scale protein expression, purification, 
    crystallization, structure determination, and structure analysis will be considered advantageous. Experience 
    in the field of intracellular transport or posttranslational modifications would be a plus.
    
    [Contract]
    The contract will be issued on a yearly basis with possible extensions. The future employee will benefit 
    from the social insurance, travel allowance and assistance with housing in accordance with the institute 
    restrictions.
    
    [Start of the contract]
    Ideally, the contract will start from April 2010. Nevertheless, the exact starting date stays open to 
    discussion with the candidate.
    
    [Applications]
    To apply, please send a cover letter, CV (in English) with a summary of your previous work and research 
    skills (A4, 1-2 sheets), reprints of your key papers, your research aspirations (A4, 1-2 sheets), and the 
    contact information of two professional references. When possible, the required documents should be 
    submitted by e-mail.
    
    [Inquiries and contact information]
    When possible, the candidates should apply by e-mail. Please address all communications to Mrs. Ishikawa 
    Gin (gin.ishikawa@kek.jp).
    
    Prof. Soichi Wakatsuki
    Structural Biology Research Center,
    Photon Factory, Institute of Materials Structure Science,
    High Energy Accelerator Research Organization (KEK).
    1-1 Oho, Tsukuba, Ibaraki, 305-0801, Japan.
    e-mail: soichi.wakatsuki@kek.jp
    


    Postdoctoral position available

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 30 January, 2010

    PDBe (the Protein Data Bank in Europe at the EBI in Cambridge, UK) is looking for an NMR Project Leader to 
    succeed Dr Wim Vranken who is coming to the end of his 9 years (the maximum allowed under EMBL rules). This 
    is a challenging and exciting opportunity for a PhD (with 3-6 years of post-doctoral experience in both 
    experimental and computational NMR on biomacromolecules) to make an impact on how the scientific community 
    archives, analyses and validates NMR data on biomacromolecules. The successful candidate will overlap for 
    several months with Dr Vranken so that the transition will be smooth.
    
    Please see the job ad on the EMBL website for further details about the position and how to apply: 
    http://www.embl.de/aboutus/jobs/jobs_embl_ebi_hinxton/2009/w_09_077_ebi/
    
    Not an NMR person?
    ------------------
    
    We are also looking for a database engineer with Oracle skills (http://www.embl.de/aboutus/jobs/jobs_embl_ebi_hinxton/2009/w_09_078_ebi/) 
    and we will soon advertise positions for two scientific programmers or software engineers, one to work on new 
    developments for the Electron Microscopy Data Bank (EMDB) and another to work on database integration (with 
    other core EBI databases) as well as the development of new ways to access the structural archive. In 2010, 
    there will be further vacancies, among others for a PDB annotator and another database engineer. So keep 
    checking the relevant part of the EMBL job site regularly: http://www.embl.de/aboutus/jobs/index.php?select_emblSite=5
    


    Post-doctoral position, IFOM-IEO-CAMPUS, Milan

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 30 January, 2010

    
    Post doctoral position available from January 2010.
    
    Laboratory: Prof. Francesco Blasi, IFOM (Foundation FIRC Institute of MolecularOncology), at the IFOM-IEO Campus, 
    Milano, Italy.http://www.ifom-ieo-campus.it/
    
    Project. Crystallization and structural analysis of the Prep1-Pbx1-DNA complex.
    
    Prep1 and Pbx1 are homeodomain proteins that interact to bind DNA andaffect developmental processes by 
    regulating the expression of Hox genes.Biochemical analysis has established the presence of N-terminal 
    regions in bothproteins required for the interaction. On the other hand at the C-termini ofboth proteins 
    contain the homeodomain that is the actual DNA-binding region.
    The interest in solving the structure of the Prep1-Pbx1-DNA complex, inaddition, lies in the novelty of 
    the domains involved for which no X-raystructure is available. Moreover, since both Prep1 and Pbx1 belong 
    to a familyof proteins, the involved domains are conserved in the other members andtherefore modeling will 
    allow to re-construct a series of structures, withpotential impact also in terms of drug targets.
    
    State of advancement of the project. The project will capitalize on previouswork in which a large number 
    of constructs and vectors has been analyzed, aswell as several purification procedures. We are now at a 
    stage in which severaldifferent constructs expressing at high level soluble protein complexes havebeen 
    produced and reliable purification procedures have been established. Thework to be done will be to search 
    for suitable crystallization procedures andto solve the X-ray structure. Conservatively, we feel that this 
    can becertainly achieved within two years
    
    Salary. At the IFOM-IEO Campus, post-doctoral salaries ranges within24000-36000?/yr. Further information 
    as to fringe benefits etc can be found atthe Campus web Site. 


    PhD position available

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 30 January, 2010

    PhD Position in Structural Biology, Wuerzburg, Germany
    
    A PhD position in structural biology is available in the group of Prof. Utz Fischer at 
    the Institute of Biochemistry, Biocentre of the Julius Maximilans-University, 
    Wuerzburg/Germany.
    
    The successful applicant will work on the crystallographic structure determination of 
    the Survival Motor Neuron (SMN) complex, the key player during the pathogenesis of 
    Spinal Muscular Atrophy (SMA). Protocols for bacterial expression and reconstitution 
    of the SMN complex are established and first crystals are already available.
    
    Please send your application including a letter of interest, curriculum vitae, academic 
    certificates and the names and contact details of two referees to:
    
    
    Dr. Clemens Grimm
    e-mail: Clemens.Grimm@biozentrum.uni-wuerzburg.de
    Institut für Biochemie
    Biozentrum der Universität Würzburg
    Am Hubland
    D-97074 Würzburg
    Germany
    
    web: www.biozentrum.de
    


    Postdoctoral position available

    Date posted: 6 November, 2009

    Deadline for applications: unknown

    Announcement will be removed: 30 January, 2010

    Postdoctoral Research Assistant at the Max-Delbrück-Centrum, (MDC) Berlin, Germany
    
    The Max-Delbrück-Centrum (MDC) in Berlin-Buch is looking for a
    Postdoctoral Research Assistant for Macromolecular Structure and
    Interaction to support the operation of the MX beamlines located at the
    BESSY II storage ring (headed by Dr. Uwe Müller, BESSY/HZB) and to
    conduct research at the MDC under the guidance of Dr. Manfred S. Weiss
    (BESSY/HZB) and Prof. Dr. Udo Heinemann (MDC). BESSY/HZB collaborates
    with the MDC in Berlin-Buch in operating three state-of-the-art
    experimental stations for bio-macromolecular crystallography at one of
    the world's most modern synchrotron radiation sources for VUV and soft
    X-rays.
    
    Description:
    The successful candidate will support MX beamline users in data
    collection and analysis, participate in the development, implementation
    and commissioning of MX beamline instrumentation, and pursue his/her own
    research in the fields of Macromolecular Structure and Interaction.
    
    Requirements:
    Applicants should hold a Ph.D. in either biological, chemical or physical
    sciences and have a strong background in all aspects of
    bio-macromolecular crystallography, in particular in the use of the
    relevant computer programs. The position also requires the documented
    ability to conduct independent research as well as excellent
    communication and interpersonal skills.
    
    Salary:
    The salary will be based on German Federal TV-D E13.
    
    Entry:
    The position is available immediately.
    
    Limitation:
    We are initially offering a three-year contract with the possibility of
    an extension.
    
    Disabled persons with same qualification are given preference. Disabled
    persons with same qualification are given preference.
    
    Applications under the reference number 10129/2009 should include a
    cover letter, curriculum vita, a publication list, and a detailed
    summary of research experience and interests.  Electronic submissions
    organized within a single pdf-file and inquiries may be addressed to:
    umue@bessy.de
    
    


    PhD positions available

    Date posted: 3 November, 2009

    Deadline for applications: 26 January, 2010

    Announcement will be removed: 27 January, 2010

    Get on target to a career in the biomedical sciences!
    
    "la Caixa"/IRB Barcelona International PhD Programme fellowships
    
    IRB Barcelona is an independent, non-profit research institution engaged in
    basic and applied biomedical sciences, located at the Parc Cient?fic de
    Barcelona on the University of Barcelona campus.
    
    We provide students in the life sciences from across the world with the
    opportunity to do training and research toward their degree in a unique
    international and multidisciplinary scientific environment.
    
    A total of 10 doctoral fellowships are available, under the auspices of "la
    Caixa", the third largest Spanish financial institution.
    
    Chemistry students and structural and computational biologists are
    encouraged to apply.
    
    Open to students in the last year of their undergraduate studies, too!
    
    
    
    Deadline for applications: January 26, 2010
    
    
    More information and application forms can be found at
    http://www.irbbarcelona.org/index.php/en/training-and-jobs
    
    


    SBNet Latest update at 25 January, 2010.