Welcome to HIC-Up, the Hetero-compound Information Centre - Uppsala, a freely accessible resource for structural biologists who are dealing dealing with hetero-compounds ("small molecules").
This service is provided and maintained by Gerard Kleywegt at the Department of Cell and Molecular Biology, Uppsala University.
This site contains information about hetero-compounds encountered in files from the Protein Data Bank (PDB). It is updated once or twice a year.
If you use information from this site in your publications, please cite one of the following papers:
For every compound, a subset of the following information is available:
There are various ways in which you try to locate a particular compound:
The first release of HIC-Up was in September, 1997. Prior to that, a repository with X-PLOR topology and parameter entries (automatically generated with XPLO2D) was maintained in Uppsala, with a mirror at Yale, and a separate repository with O-related information existed as well.
The number of entries in HIC-Up has developed as follows:
Release | Date | Entries |
---|---|---|
12.1 | 2008-03-01 | 7870 |
11.2 | 2007-06-01 | 7452 |
11.1 | 2007-01-04 | 7078 |
10.2 | 2006-07-26 | 6613 |
10.1 | 2006-04-03 | 6347 |
9.1 | 2005-01-17 | 5384 |
8.2 | 2004-06-17 | 4968 |
8.1 | 2004-02-20 | 4669 |
7.3 | 2003-11-11 | 4511 |
7.2 | 2003-04-17 | 4119 |
7.1 | 2003-01-15 | 3941 |
6.1 | 2002-07-04 | 3666 |
5.3 | 2001-12-01 | 3416 |
5.2 | 2001-09-06 | 3296 |
5.1 | 2001-03-27 | 3078 |
5.0 | 2001-01-04 | 2971 |
4.0 | 2000-07-09 | 2640 |
3.1 | 1999-11-11 | 2290 |
3.0 | 1999-04-01 | 1981 |
2.0 | 1998-07-27 | 1649 |
1.1 | 1997-12-12 | 1433 |
1.0 | 1997-09-30 | 1100 |
HIC-Up - The Hetero-compound Information Centre - Uppsala |
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