Bke2 Biochemistry Exercises

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Group exercise: Transcription and gene regulation

  1. How does an RNA polymerase "know" where on a DNA molecule to start the transcription of a gene into RNA?

  2. Why is it so important for organisms to be able to regulate the expression of their genes? Take as examples: i) a multicellular organism, ii) your favorite bacterium - and discuss the different challenges they face.

  3. Describe different ways bacteria use to regulate gene transcription, taking the lactose (lac) operon as an example.

Reading material: Horton, Chapter 21 (Stryer chapter 5, 33, 36 & 37; Alberts chapter 6, 8, & 9)

Lectures:
Transcription, gene regulation

Links:
Suggested answers

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Exercise by Andrea Hinas
Page updated 2004.09.27 by jerry@xray.bmc.uu.se
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